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DDB1 E3 ligase controls dietary fructose-induced ChREBPα stabilization and liver steatosis via CRY1
Fructose over-consumption contributes to the development of liver steatosis in part by stimulating ChREBPα-driven de novo lipogenesis. However, the mechanisms by which fructose activates ChREBP pathway remain largely undefined. Here we performed affinity purification of ChREBPα followed by mass spec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282961/ https://www.ncbi.nlm.nih.gov/pubmed/32246987 http://dx.doi.org/10.1016/j.metabol.2020.154222 |