Desaturase specificity is controlled by the physicochemical properties of a single amino acid residue in the substrate binding tunnel

Membrane fatty acyl desaturases (mFAD) are ubiquitous enzymes in eukaryotes. They introduce double bonds into fatty acids (FAs), producing structurally diverse unsaturated FAs which serve as membrane lipid components or precursors of signaling molecules. The mechanisms controlling enzymatic specific...

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Detalles Bibliográficos
Autores principales: Buček, Aleš, Vazdar, Mario, Tupec, Michal, Svatoš, Aleš, Pichová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283083/
https://www.ncbi.nlm.nih.gov/pubmed/32542106
http://dx.doi.org/10.1016/j.csbj.2020.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283083/
https://www.ncbi.nlm.nih.gov/pubmed/32542106
http://dx.doi.org/10.1016/j.csbj.2020.05.011

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