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Desaturase specificity is controlled by the physicochemical properties of a single amino acid residue in the substrate binding tunnel
Membrane fatty acyl desaturases (mFAD) are ubiquitous enzymes in eukaryotes. They introduce double bonds into fatty acids (FAs), producing structurally diverse unsaturated FAs which serve as membrane lipid components or precursors of signaling molecules. The mechanisms controlling enzymatic specific...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283083/ https://www.ncbi.nlm.nih.gov/pubmed/32542106 http://dx.doi.org/10.1016/j.csbj.2020.05.011 |