Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells

A leukemic in vitro model produced by transducing Cord Blood derived-hematopoietic CD34(+) cells with the MLL-AF9 translocation resulting in the oncogenic fusion protein, is used to assess for sensitivity to Zoledronic acid. These cells are practically immortalized and are of myeloid origin. Prolife...

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Detalles Bibliográficos
Autores principales: Chiarella, Emanuela, Codispoti, Bruna, Aloisio, Annamaria, Cosentino, Emanuela G., Scicchitano, Stefania, Montalcini, Ylenia, Lico, Daniela, Morrone, Giovanni, Mesuraca, Maria, Bond, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283156/
https://www.ncbi.nlm.nih.gov/pubmed/32529062
http://dx.doi.org/10.1016/j.heliyon.2020.e04020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283156/
https://www.ncbi.nlm.nih.gov/pubmed/32529062
http://dx.doi.org/10.1016/j.heliyon.2020.e04020

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