Pneumonia-induced endothelial amyloids reduce dendritic spine density in brain neurons

Pseudomonas aeruginosa pneumonia elicits endothelial cell release of cytotoxic amyloids that can be recovered from the bronchoalveolar lavage and cerebrospinal fluids of critically ill patients. Introduction of these cytotoxic amyloids into the lateral ventricle impairs learning and memory in mice....

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Detalles Bibliográficos
Autores principales: Scott, Allison M., Jager, Alexandrea C., Gwin, Meredith, Voth, Sarah, Balczon, Ron, Stevens, Troy, Lin, Mike T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283224/
https://www.ncbi.nlm.nih.gov/pubmed/32518286
http://dx.doi.org/10.1038/s41598-020-66321-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283224/
https://www.ncbi.nlm.nih.gov/pubmed/32518286
http://dx.doi.org/10.1038/s41598-020-66321-1

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