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Pneumonia-induced endothelial amyloids reduce dendritic spine density in brain neurons
Pseudomonas aeruginosa pneumonia elicits endothelial cell release of cytotoxic amyloids that can be recovered from the bronchoalveolar lavage and cerebrospinal fluids of critically ill patients. Introduction of these cytotoxic amyloids into the lateral ventricle impairs learning and memory in mice....
Autores principales: | Scott, Allison M., Jager, Alexandrea C., Gwin, Meredith, Voth, Sarah, Balczon, Ron, Stevens, Troy, Lin, Mike T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283224/ https://www.ncbi.nlm.nih.gov/pubmed/32518286 http://dx.doi.org/10.1038/s41598-020-66321-1 |
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