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Ki-67 response-guided preoperative chemotherapy for HER2-positive breast cancer: results of a randomised Phase 2 study

BACKGROUND: The effectiveness of a therapeutic strategy that switches chemotherapy, based on Ki-67 tumour expression after initial therapy, relative to that of standard chemotherapy, has not been evaluated. METHODS: Patients were randomly assigned to the control arm or the Ki-67 response-guided arm...

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Detalles Bibliográficos
Autores principales: Mukai, Hirofumi, Yamaguchi, Takeshi, Takahashi, Masato, Hozumi, Yasuo, Fujisawa, Tomomi, Ohsumi, Shozo, Akabane, Hiromitsu, Nishimura, Reiki, Takashima, Tsutomu, Park, Youngjin, Sagara, Yasuaki, Toyama, Tatsuya, Imoto, Shigeru, Mizuno, Toshiro, Yamashita, Satoshi, Fujii, Satoshi, Uemura, Yukari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283228/
https://www.ncbi.nlm.nih.gov/pubmed/32238920
http://dx.doi.org/10.1038/s41416-020-0815-9