Cargando…

Chronic in vivo exposure to Helicobacter pylori VacA: Assessing the efficacy of automated and long-term intragastric toxin infusion

Helicobacter pylori (Hp) secrete VacA, a diffusible pore-forming exotoxin that is epidemiologically linked to gastric disease in humans. In vitro studies indicate that VacA modulates gastric epithelial and immune cells, but the in vivo contributions of VacA as an important determinant of Hp coloniza...

Descripción completa

Detalles Bibliográficos
Autores principales: Holland, Robin L., Bosi, Kristopher D., Harpring, Gregory H., Luo, Jiayi, Wallig, Matthew, Phillips, Heidi, Blanke, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283276/
https://www.ncbi.nlm.nih.gov/pubmed/32518315
http://dx.doi.org/10.1038/s41598-020-65787-3