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Chronic in vivo exposure to Helicobacter pylori VacA: Assessing the efficacy of automated and long-term intragastric toxin infusion
Helicobacter pylori (Hp) secrete VacA, a diffusible pore-forming exotoxin that is epidemiologically linked to gastric disease in humans. In vitro studies indicate that VacA modulates gastric epithelial and immune cells, but the in vivo contributions of VacA as an important determinant of Hp coloniza...
Autores principales: | Holland, Robin L., Bosi, Kristopher D., Harpring, Gregory H., Luo, Jiayi, Wallig, Matthew, Phillips, Heidi, Blanke, Steven R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283276/ https://www.ncbi.nlm.nih.gov/pubmed/32518315 http://dx.doi.org/10.1038/s41598-020-65787-3 |
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