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Rational Design of a Protein Kinase A Nuclear-cytosol Translocation Reporter
Protein Kinase A (PKA) exists as a tetrameric holoenzyme which activates with increase of cAMP and plays an important role in many physiological processes including cardiac physiology, neuronal development, and adipocyte function. Although this kinase has been the subject of numerous biosensor desig...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283302/ https://www.ncbi.nlm.nih.gov/pubmed/32518322 http://dx.doi.org/10.1038/s41598-020-66349-3 |