Cargando…

Rational Design of a Protein Kinase A Nuclear-cytosol Translocation Reporter

Protein Kinase A (PKA) exists as a tetrameric holoenzyme which activates with increase of cAMP and plays an important role in many physiological processes including cardiac physiology, neuronal development, and adipocyte function. Although this kinase has been the subject of numerous biosensor desig...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Allen K., Wu, Helen D., Inoue, Takanari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283302/
https://www.ncbi.nlm.nih.gov/pubmed/32518322
http://dx.doi.org/10.1038/s41598-020-66349-3