Cardio-renal protective effect of the xanthine oxidase inhibitor febuxostat in the 5/6 nephrectomy model with hyperuricemia

Although hyperuricemia has been shown to be associated with the progression of cardiovascular disorder and chronic kidney disease (CKD), there is conflicting evidence as to whether xanthine oxidase (XO) inhibitors confer organ protection besides lowering serum urate levels. In this study, we address...

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Detalles Bibliográficos
Autores principales: Omizo, Hiroki, Tamura, Yoshifuru, Morimoto, Chikayuki, Ueno, Masaki, Hayama, Yuto, Kuribayashi-Okuma, Emiko, Uchida, Shunya, Shibata, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283314/
https://www.ncbi.nlm.nih.gov/pubmed/32518351
http://dx.doi.org/10.1038/s41598-020-65706-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283314/
https://www.ncbi.nlm.nih.gov/pubmed/32518351
http://dx.doi.org/10.1038/s41598-020-65706-6

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