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Stearoyl-CoA-desaturase-1 regulates gastric cancer stem-like properties and promotes tumour metastasis via Hippo/YAP pathway

BACKGROUND: Stearoyl-CoA desaturase-1 (SCD1) is reported to play essential roles in cancer stemness among several cancers. Our previous research revealed significant overexpression of SCD1 in primary gastric cancer stem cells (GCSCs), with its functional role still unknown. METHODS: We stably establ...

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Detalles Bibliográficos
Autores principales: Gao, Yunhe, Li, Jiyang, Xi, Hongqing, Cui, Jianxin, Zhang, Kecheng, Zhang, Jiabing, Zhang, Yanmei, Xu, Wei, Liang, Wenquan, Zhuang, Ziwei, Wang, Pengpeng, Qiao, Zhi, Wei, Bo, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283337/
https://www.ncbi.nlm.nih.gov/pubmed/32350414
http://dx.doi.org/10.1038/s41416-020-0827-5