Cargando…

Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants

Vascularized composite allotransplantation (VCA) allows tissue replacement after devastating loss but is currently limited in application and may be more widely performed if maintenance immunosuppression was not essential for graft acceptance. We tested whether peri-transplant costimulation blockade...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Liqing, Wang, Zhonglin, Han, Rongxiang, Samanta, Arabinda, Ge, Guanghui, Levin, L. Scott, Levine, Matthew H., Hancock, Wayne W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283338/ https://www.ncbi.nlm.nih.gov/pubmed/32518311 http://dx.doi.org/10.1038/s41598-020-66139-x

Ejemplares similares

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function
por: Huang, Jianbing, et al.
Publicado: (2017)

Costimulation Blockade Induces Foxp3(+) Regulatory T Cells to Human Embryonic Stem Cells
por: Ljung, Karin, et al.
Publicado: (2013)

Two Lysines in the Forkhead Domain of Foxp3 Are Key to T Regulatory Cell Function
por: Liu, Yujie, et al.
Publicado: (2012)

A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells
por: Di Giorgio, Eros, et al.
Publicado: (2021)

Costimulation Blockade in Kidney Transplantation: An Update
por: Malvezzi, Paolo, et al.
Publicado: (2016)

Costimulation Blockade in Vascularized Composite Allotransplantation
por: Giannis, Dimitrios, et al.
Publicado: (2020)

Costimulation Blockade in Kidney Transplant Recipients
por: van der Zwan, Marieke, et al.
Publicado: (2019)

HDAC10 deletion promotes Foxp3(+) T-regulatory cell function
por: Dahiya, Satinder, et al.
Publicado: (2020)

Predicting clinical response to costimulation blockade in autoimmunity
por: Edner, Natalie M, et al.
Publicado: (2020)

Costimulation blockade and Tregs in solid organ transplantation
por: Muckenhuber, Moritz, et al.
Publicado: (2022)

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells
por: Liu, Yujie, et al.
Publicado: (2019)

The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation
por: Samy, Kannan P., et al.
Publicado: (2017)

Modulation of LIGHT-HVEM Costimulation Prolongs Cardiac Allograft Survival
por: Ye, Qunrui, et al.
Publicado: (2002)

CXCR4 acts as a costimulator during thymic β selection
por: Trampont, Paul C., et al.
Publicado: (2009)

ALEFACEPT PROMOTES COSTIMULATION BLOCKADE BASED ALLOGRAFT SURVIVAL IN PRIMATES
por: Weaver, T.A., et al.
Publicado: (2009)

Corrigendum to “The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation”
por: Samy, Kannan P., et al.
Publicado: (2018)

T Cell Costimulation Blockade Blunts Age-Related Heart Failure
por: Martini, Elisa, et al.
Publicado: (2020)

Minor Antigen Disparities Impede Induction of Long Lasting Chimerism and Tolerance through Bone Marrow Transplantation with Costimulation Blockade
por: Bigenzahn, Sinda, et al.
Publicado: (2016)

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3 + T-regulatory Cell Function and Promotes Antitumor Immunity
por: Wang, Liqing, et al.
Publicado: (2016)

T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis
por: Boleto, Gonçalo, et al.
Publicado: (2018)

T cell costimulation blockade blunts pressure overload-induced heart failure
por: Kallikourdis, Marinos, et al.
Publicado: (2017)

Combination of isoform-selective histone/protein deacetylase inhibitors improves Foxp3+ T-regulatory cell function
por: Beier, Ulf H., et al.
Publicado: (2012)

Costimulation pathway blockade in kidney transplant recipients with de-novo rheumatoid arthritis
por: Sheta, Mohamed, et al.
Publicado: (2017)

Three Distinct Domains Contribute to Nuclear Transport of Murine Foxp3
por: Hancock, Wayne W., et al.
Publicado: (2009)

Targeting Sirtuin-1 Alleviates Experimental Autoimmune Colitis by Induction of Foxp3+ T-Regulatory Cells: Sirt1 targeting alleviates autoimmune colitis
por: Akimova, Tatiana, et al.
Publicado: (2014)

Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival
por: Emamaullee, Juliet A., et al.
Publicado: (2010)

Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes
por: Edner, Natalie M., et al.
Publicado: (2020)

Inhibition of p300 impairs Foxp3(+) T-regulatory cell function and promotes anti-tumor immunity
por: Liu, Yujie, et al.
Publicado: (2013)

Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice
por: Mangada, Julie, et al.
Publicado: (2009)

Direct comparisons of T cell costimulation and checkpoint blockade in the setting of tumor-targeted monoclonal antibody therapy
por: Khalil, Danny, et al.
Publicado: (2015)

Linked sensitization by memory CD4(+) T cells prevents costimulation blockade–induced transplantation tolerance
por: Andrade, Michael S., et al.
Publicado: (2022)

Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
por: Wang, Chun Jing, et al.
Publicado: (2022)

Recruitment of Foxp3(+) T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
por: Lee, Iris, et al.
Publicado: (2005)

New battlefields for costimulation
por: Martin-Orozco, Natalia, et al.
Publicado: (2006)

1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept
por: Gardner, David H., et al.
Publicado: (2015)

ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity
por: Soldevilla, Mario Martínez, et al.
Publicado: (2019)

Successful long-term management of recurrent focal segmental glomerulosclerosis after kidney transplantation with costimulation blockade
por: Mühlbacher, Thomas, et al.
Publicado: (2020)

In vivo Treg expansion under costimulation blockade targets early rejection and improves long‐term outcome
por: Schwarz, Christoph, et al.
Publicado: (2021)

IL-21 Biased Alemtuzumab Induced Chronic Antibody-Mediated Rejection Is Reversed by LFA-1 Costimulation Blockade
por: Kwun, Jean, et al.
Publicado: (2018)

Author Correction: Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
por: Wang, Chun Jing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ul42bauln2mlg9lfqqmb21sf6g