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CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment

The sequential generation of layer-specific cortical neurons requires radial glia cells (RGCs) to precisely balance self-renewal and lineage commitment. While specific cell-cycle phases have been associated with these decisions, the mechanisms linking the cell-cycle machinery to cell-fate commitment...

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Detalles Bibliográficos
Autores principales: Hagey, Daniel W., Topcic, Danijal, Kee, Nigel, Reynaud, Florie, Bergsland, Maria, Perlmann, Thomas, Muhr, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283355/
https://www.ncbi.nlm.nih.gov/pubmed/32518258
http://dx.doi.org/10.1038/s41467-020-16597-8