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Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling

Bacterial nucleoid remodeling dependent on conserved histone-like protein, HU is one of the determining factors in global gene regulation. By imaging of near-native, unlabeled E. coli cells by soft X-ray tomography, we show that HU remodels nucleoids by promoting the formation of a dense condensed c...

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Detalles Bibliográficos
Autores principales: Remesh, Soumya G., Verma, Subhash C., Chen, Jian-Hua, Ekman, Axel A., Larabell, Carolyn A., Adhya, Sankar, Hammel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283360/
https://www.ncbi.nlm.nih.gov/pubmed/32518228
http://dx.doi.org/10.1038/s41467-020-16724-5