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Modeling of Mechanosensing Mechanisms Reveals Distinct Cell Migration Modes to Emerge From Combinations of Substrate Stiffness and Adhesion Receptor–Ligand Affinity
Mesenchymal cell migration is an integral process in development and healing. The process is regulated by both mechanical and biochemical properties. Mechanical properties of the environment are sensed through mechanosensing, which consists of molecular responses mediated by mechanical signals. We d...
Autores principales: | Vargas, Diego A., Gonçalves, Inês G., Heck, Tommy, Smeets, Bart, Lafuente-Gracia, Laura, Ramon, Herman, Van Oosterwyck, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283468/ https://www.ncbi.nlm.nih.gov/pubmed/32582650 http://dx.doi.org/10.3389/fbioe.2020.00459 |
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