Emerging role of PTEN loss in evasion of the immune response to tumours

Mutations in PTEN activate the phosphoinositide 3-kinase (PI3K) signalling network, leading to many of the characteristic phenotypic changes of cancer. However, the primary effects of this gene on oncogenesis through control of the PI3K–AKT–mammalian target of rapamycin (mTOR) pathway might not be t...

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Detalles Bibliográficos
Autores principales: Vidotto, Thiago, Melo, Camila Morais, Castelli, Erick, Koti, Madhuri, dos Reis, Rodolfo Borges, Squire, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283470/
https://www.ncbi.nlm.nih.gov/pubmed/32327707
http://dx.doi.org/10.1038/s41416-020-0834-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283470/
https://www.ncbi.nlm.nih.gov/pubmed/32327707
http://dx.doi.org/10.1038/s41416-020-0834-6

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