Cargando…

Deficiency of STING Promotes Collagen-Specific Antibody Production and B Cell Survival in Collagen-Induced Arthritis

The levels of interferon-alpha are high in the serum and synovial fluid of rheumatoid arthritis (RA) patients. Activation of the stimulator of type I interferon genes (STING) mediates the productions of type I interferon and promotes chronic inflammation. STING plays a significant role in autoimmune...

Descripción completa

Detalles Bibliográficos
Autores principales: Tansakul, Mookmanee, Thim-uam, Arthid, Saethang, Thammakorn, Makjaroen, Jiradej, Wongprom, Benjawan, Pisitkun, Trairak, Pisitkun, Prapaporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283782/
https://www.ncbi.nlm.nih.gov/pubmed/32582187
http://dx.doi.org/10.3389/fimmu.2020.01101