In vitro Mechanistic Exploration of Novel Spiropyrrolidine Heterocyclic Hybrids as Anticancer Agents

Novel spiro acenaphthylene pyrrolo[1,2-b]isoquinoline/pyrrolidine hybrids have been achieved through Pictet-Spengler/Eschweiler-Clarke reactions depending on the substitution in the benzyl ring. The in vitro biological efficacy of N-methyl spiropyrrolidine derivatives toward different cancer and non...

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Detalles Bibliográficos
Autores principales: Kumar, Raju Suresh, Almansour, Abdulrahman I., Arumugam, Natarajan, Mohammad, Faruq, Kumar, Raju Ranjith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283928/
https://www.ncbi.nlm.nih.gov/pubmed/32582638
http://dx.doi.org/10.3389/fchem.2020.00465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283928/
https://www.ncbi.nlm.nih.gov/pubmed/32582638
http://dx.doi.org/10.3389/fchem.2020.00465

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