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Pediatric Diffuse Midline Gliomas H3 K27M-Mutant and Non-Histone Mutant Midline High-Grade Gliomas in Neurofibromatosis Type 1 in Comparison With Non-Syndromic Children: A Single-Center Pilot Study

Background: Pediatric neurofibromatosis type 1 (NF1) patients rarely develop aggressive central nervous system tumors. Among high-grade gliomas (HGGs), histone mutant diffuse midline gliomas (DMGs H3 K27M-mutant) have exceptionally been reported. The aim of this retrospectives single-center study wa...

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Detalles Bibliográficos
Autores principales: Garibotto, Federica, Madia, Francesca, Milanaccio, Claudia, Verrico, Antonio, Piccardo, Arnoldo, Tortora, Domenico, Piatelli, Gianluca, Diana, Maria Cristina, Capra, Valeria, Garrè, Maria Luisa, Rossi, Andrea, Morana, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283930/
https://www.ncbi.nlm.nih.gov/pubmed/32582540
http://dx.doi.org/10.3389/fonc.2020.00795