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CD47 decline in pancreatic islet cells promotes macrophage-mediated phagocytosis in type I diabetes
BACKGROUND: Type I diabetes (T1D) is characterized by insulin loss caused by inflammatory cells that excessively infiltrate and destroy the pancreas, resulting in dysregulation of tissue homeostasis, mechanobiological properties, and the immune response. The streptozotocin (STZ)-induced mouse model...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Baishideng Publishing Group Inc
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284019/ https://www.ncbi.nlm.nih.gov/pubmed/32547698 http://dx.doi.org/10.4239/wjd.v11.i6.239 |