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Comparison of NGS panel and Sanger sequencing for genotyping CAG repeats in the AR gene

BACKGROUND: The androgen receptor (AR) is a nuclear receptor, encoded by the AR gene on the X chromosome. Within the first exon of the AR gene, two short tandem repeats (STR), CAG and GGC, are a source of polymorphism in the population. Therefore, high‐throughput methods for screening AR, such as ne...

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Detalles Bibliográficos
Autores principales: Rocca, Maria Santa, Ferrarini, Margherita, Msaki, Aichi, Vinanzi, Cinzia, Ghezzi, Marco, De Rocco Ponce, Maurizio, Foresta, Carlo, Ferlin, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284049/
https://www.ncbi.nlm.nih.gov/pubmed/32216057
http://dx.doi.org/10.1002/mgg3.1207