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A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment

AIMS: Inflammatory response plays a pivotal role in the pathophysiological process of intervertebral disc degeneration (IDD). A20 (also known as tumour necrosis factor alpha-induced protein 3 (TNFAIP3)) is a ubiquitin-editing enzyme that restricts nuclear factor-kappa B (NF-κB) signalling. A20 preve...

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Detalles Bibliográficos
Autores principales: Peng, Xin, Zhang, Cong, Bao, Jun-Ping, Zhu, Lei, Shi, Rui, Xie, Zhi-Yang, Wang, Feng, Wang, Kun, Wu, Xiao-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284293/
https://www.ncbi.nlm.nih.gov/pubmed/32566144
http://dx.doi.org/10.1302/2046-3758.95.BJR-2019-0230.R1