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A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment
AIMS: Inflammatory response plays a pivotal role in the pathophysiological process of intervertebral disc degeneration (IDD). A20 (also known as tumour necrosis factor alpha-induced protein 3 (TNFAIP3)) is a ubiquitin-editing enzyme that restricts nuclear factor-kappa B (NF-κB) signalling. A20 preve...
Autores principales: | Peng, Xin, Zhang, Cong, Bao, Jun-Ping, Zhu, Lei, Shi, Rui, Xie, Zhi-Yang, Wang, Feng, Wang, Kun, Wu, Xiao-tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284293/ https://www.ncbi.nlm.nih.gov/pubmed/32566144 http://dx.doi.org/10.1302/2046-3758.95.BJR-2019-0230.R1 |
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