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Redox-Sensitive Linear and Cross-Linked Cystamine-Based Polymers for Colon-Targeted Drug Delivery: Design, Synthesis, and Characterisation

Cystamine-based polymers may help to achieve controlled and targeted drug delivery to the colon due to their susceptibility to breakage of the disulfide linkage in the low redox potential environment of the colon. In this study, two linear cystamine-based polymers with similar repeating units (LP1 a...

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Detalles Bibliográficos
Autores principales: Ng, Yoke Mooi, Mat Yusuf, Siti Nur Aishah, Chiu, Hock Ing, Lim, Vuanghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284438/
https://www.ncbi.nlm.nih.gov/pubmed/32443633
http://dx.doi.org/10.3390/pharmaceutics12050461