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Effect of Double Substitution in Cationic Chitosan Derivatives on DNA Transfection Efficiency

Recently, much effort has been expended on the development of non-viral gene delivery systems based on polyplexes of nucleic acids with various cationic polymers. Natural polysaccharide derivatives are promising carriers due to their low toxicity. In this work, chitosan was chemically modified by a...

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Detalles Bibliográficos
Autores principales: Badazhkova, Veronika D., Raik, Sergei V., Polyakov, Dmitry S., Poshina, Daria N., Skorik, Yury A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284465/
https://www.ncbi.nlm.nih.gov/pubmed/32380700
http://dx.doi.org/10.3390/polym12051057