Elevated Glucose and Insulin Levels Decrease DHA Transfer across Human Trophoblasts via SIRT1-Dependent Mechanism

Gestational diabetes mellitus (GDM) results in reduced docosahexaenoic acid (DHA) transfer to the fetus, likely due to placental dysfunction. Sirtuin-1 (SIRT1) is a nutrient sensor and regulator of lipid metabolism. This study investigated whether the high glucose and insulin condition of GDM regula...

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Detalles Bibliográficos
Autores principales: Mishra, Jay S., Zhao, Hanjie, Hattis, Sari, Kumar, Sathish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284516/
https://www.ncbi.nlm.nih.gov/pubmed/32365792
http://dx.doi.org/10.3390/nu12051271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284516/
https://www.ncbi.nlm.nih.gov/pubmed/32365792
http://dx.doi.org/10.3390/nu12051271

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