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Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?

Epigenetic alterations, as a cancer hallmark, are associated with cancer initiation, progression and aggressiveness. Considering, however, that these alterations are reversible, drugs that target epigenetic machinery may have an inhibitory effect upon cancer treatment. The traditional drug discovery...

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Detalles Bibliográficos
Autores principales: Moreira-Silva, Filipa, Camilo, Vânia, Gaspar, Vítor, Mano, João F., Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284583/
https://www.ncbi.nlm.nih.gov/pubmed/32365701
http://dx.doi.org/10.3390/pharmaceutics12050410