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Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?
Epigenetic alterations, as a cancer hallmark, are associated with cancer initiation, progression and aggressiveness. Considering, however, that these alterations are reversible, drugs that target epigenetic machinery may have an inhibitory effect upon cancer treatment. The traditional drug discovery...
Autores principales: | Moreira-Silva, Filipa, Camilo, Vânia, Gaspar, Vítor, Mano, João F., Henrique, Rui, Jerónimo, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284583/ https://www.ncbi.nlm.nih.gov/pubmed/32365701 http://dx.doi.org/10.3390/pharmaceutics12050410 |
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