Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), is a selective anticancer cytokine capable of exerting a targeted therapy approach. Disappointingly, recent research has highlighted the development of TRAIL resistance in cancer cells, thus minimising its usefulness in clinical setti...

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Detalles Bibliográficos
Autores principales: Obaidi, Ismael, Cassidy, Hilary, Ibáñez Gaspar, Verónica, McCaul, Jasmin, Higgins, Michael, Halász, Melinda, Reynolds, Alison L., Kennedy, Breandan N., McMorrow, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284747/
https://www.ncbi.nlm.nih.gov/pubmed/32370057
http://dx.doi.org/10.3390/biology9050092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284747/
https://www.ncbi.nlm.nih.gov/pubmed/32370057
http://dx.doi.org/10.3390/biology9050092

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