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Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL), is a selective anticancer cytokine capable of exerting a targeted therapy approach. Disappointingly, recent research has highlighted the development of TRAIL resistance in cancer cells, thus minimising its usefulness in clinical setti...

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Detalles Bibliográficos
Autores principales:	Obaidi, Ismael, Cassidy, Hilary, Ibáñez Gaspar, Verónica, McCaul, Jasmin, Higgins, Michael, Halász, Melinda, Reynolds, Alison L., Kennedy, Breandan N., McMorrow, Tara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284747/ https://www.ncbi.nlm.nih.gov/pubmed/32370057 http://dx.doi.org/10.3390/biology9050092

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