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A Comparative Study of Rat Urine (1)H-NMR Metabolome Changes Presumably Arising from Isoproterenol-Induced Heart Necrosis Versus Clarithromycin-Induced QT Interval Prolongation

Cardiotoxicity remains a challenging concern both in drug development and in the management of various clinical situations. There are a lot of examples of drugs withdrawn from the market or stopped during clinical trials due to unpredicted cardiac adverse events. Obviously, current conventional meth...

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Detalles Bibliográficos
Autores principales: Dallons, Matthieu, Delcourt, Manon, Schepkens, Corentin, Podrecca, Manuel, Colet, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284797/
https://www.ncbi.nlm.nih.gov/pubmed/32414184
http://dx.doi.org/10.3390/biology9050098