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Direct, Competitive Comparison of Linear, Monocyclic, and Bicyclic Libraries Using mRNA Display
[Image: see text] Peptide macrocyclization is typically associated with the development of higher affinity and more protease stable protein ligands, and, as such, is an important tool in peptide drug discovery. Yet, within the context of a diverse library, does cyclization give inherent advantages o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284801/ https://www.ncbi.nlm.nih.gov/pubmed/32418423 http://dx.doi.org/10.1021/acscombsci.0c00016 |