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Towards deorphanizing G protein-coupled receptors of Schistosoma mansoni using the MALAR yeast two-hybrid system

Schistosomiasis is an acute and chronic disease caused by parasitic worms of the genus Schistosoma. Treatment is solely dependent on praziquantel. In the face of the worldwide dimension, projects have been initiated to develop new chemotherapies. Due to their proven druggability, G protein-coupled r...

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Detalles Bibliográficos
Autores principales: Weth, Oliver, Haeberlein, Simone, Haimann, Martin, Zhang, Yinjie, Grevelding, Christoph G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284817/
https://www.ncbi.nlm.nih.gov/pubmed/31840628
http://dx.doi.org/10.1017/S0031182019001756