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Towards deorphanizing G protein-coupled receptors of Schistosoma mansoni using the MALAR yeast two-hybrid system
Schistosomiasis is an acute and chronic disease caused by parasitic worms of the genus Schistosoma. Treatment is solely dependent on praziquantel. In the face of the worldwide dimension, projects have been initiated to develop new chemotherapies. Due to their proven druggability, G protein-coupled r...
Autores principales: | Weth, Oliver, Haeberlein, Simone, Haimann, Martin, Zhang, Yinjie, Grevelding, Christoph G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284817/ https://www.ncbi.nlm.nih.gov/pubmed/31840628 http://dx.doi.org/10.1017/S0031182019001756 |
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