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Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

Liposomes containing copper and the copper ionophore neocuproine were prepared and characterized for in vitro and in vivo anticancer activity. Thermosensitive PEGylated liposomes were prepared with different molar ratios of 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) and hydrogenated soy...

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Detalles Bibliográficos
Autores principales: Gaál, Anikó, Garay, Tamás M., Horváth, Ildikó, Máthé, Domokos, Szöllősi, Dávid, Veres, Dániel S., Mbuotidem, Jeremiah, Kovács, Tibor, Tóvári, József, Bergmann, Ralf, Streli, Christina, Szakács, Gergely, Mihály, Judith, Varga, Zoltán, Szoboszlai, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284829/
https://www.ncbi.nlm.nih.gov/pubmed/32443790
http://dx.doi.org/10.3390/pharmaceutics12050466