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Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation
Liposomes containing copper and the copper ionophore neocuproine were prepared and characterized for in vitro and in vivo anticancer activity. Thermosensitive PEGylated liposomes were prepared with different molar ratios of 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) and hydrogenated soy...
Autores principales: | Gaál, Anikó, Garay, Tamás M., Horváth, Ildikó, Máthé, Domokos, Szöllősi, Dávid, Veres, Dániel S., Mbuotidem, Jeremiah, Kovács, Tibor, Tóvári, József, Bergmann, Ralf, Streli, Christina, Szakács, Gergely, Mihály, Judith, Varga, Zoltán, Szoboszlai, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284829/ https://www.ncbi.nlm.nih.gov/pubmed/32443790 http://dx.doi.org/10.3390/pharmaceutics12050466 |
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