The Role of Functional Excipients in Solid Oral Dosage Forms to Overcome Poor Drug Dissolution and Bioavailability

Many active pharmaceutical ingredients (APIs) exhibit poor solubility and low dissolution rates in aqueous environments such as the luminal fluids of the gastrointestinal tract. The oral bioavailability of these compounds is usually very low as a result of their poor solubility properties. In order...

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Detalles Bibliográficos
Autores principales: van der Merwe, Jannes, Steenekamp, Jan, Steyn, Dewald, Hamman, Josias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284856/
https://www.ncbi.nlm.nih.gov/pubmed/32344802
http://dx.doi.org/10.3390/pharmaceutics12050393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284856/
https://www.ncbi.nlm.nih.gov/pubmed/32344802
http://dx.doi.org/10.3390/pharmaceutics12050393

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