Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats

The potential inhibitory effect of quercetin, a major plant flavonol, on breast cancer resistance protein (BCRP) activity was investigated in this study. The presence of quercetin significantly increased the cellular accumulation and associated cytotoxicity of the BCRP substrate mitoxantrone in huma...

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Detalles Bibliográficos
Autores principales: Song, Yoo-Kyung, Yoon, Jin-Ha, Woo, Jong Kyu, Kang, Ju-Hee, Lee, Kyeong-Ryoon, Oh, Seung Hyun, Chung, Suk-Jae, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285070/
https://www.ncbi.nlm.nih.gov/pubmed/32357395
http://dx.doi.org/10.3390/pharmaceutics12050397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285070/
https://www.ncbi.nlm.nih.gov/pubmed/32357395
http://dx.doi.org/10.3390/pharmaceutics12050397

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