Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis

Animal models are a valuable tool in preclinical research. However, limited predictivity of human biological responses in the conventional models has stimulated the search for reliable preclinical tools that show translational robustness. Here, we used precision-cut kidney slices (PCKS) as a model o...

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Detalles Bibliográficos
Autores principales: Bigaeva, Emilia, Puerta Cavanzo, Nataly, Stribos, Elisabeth G. D., de Jong, Amos J., Biel, Carin, Mutsaers, Henricus A. M., Jensen, Michael S., Nørregaard, Rikke, Leliveld, Anna M., de Jong, Igle J., Hillebrands, Jan-Luuk, van Goor, Harry, Boersema, Miriam, Bank, Ruud A., Olinga, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285118/
https://www.ncbi.nlm.nih.gov/pubmed/32443499
http://dx.doi.org/10.3390/pharmaceutics12050459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285118/
https://www.ncbi.nlm.nih.gov/pubmed/32443499
http://dx.doi.org/10.3390/pharmaceutics12050459

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