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Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1

BACKGROUND: Rhomboid domain containing 1 (RHBDD1) plays a crucial role in tumorigenesis. Silibinin, which is a natural extract from milk thistle, has shown anti-tumor effects against various tumors. Here, we investigate whether silibinin affects the function of RHBDD1 in non-small cell lung cancer (...

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Detalles Bibliográficos
Autores principales: Xu, Suyan, Zhang, Hongyan, Wang, Aifeng, Ma, Yongcheng, Gan, Yuan, Li, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285460/
https://www.ncbi.nlm.nih.gov/pubmed/32528541
http://dx.doi.org/10.1186/s11658-020-00229-6