Cargando…

Silibinin suppresses epithelial–mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1

BACKGROUND: Rhomboid domain containing 1 (RHBDD1) plays a crucial role in tumorigenesis. Silibinin, which is a natural extract from milk thistle, has shown anti-tumor effects against various tumors. Here, we investigate whether silibinin affects the function of RHBDD1 in non-small cell lung cancer (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Suyan, Zhang, Hongyan, Wang, Aifeng, Ma, Yongcheng, Gan, Yuan, Li, Guofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285460/ https://www.ncbi.nlm.nih.gov/pubmed/32528541 http://dx.doi.org/10.1186/s11658-020-00229-6

Ejemplares similares

Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition
por: Kim, Joong Sun, et al.
Publicado: (2017)

Silibinin inhibits epithelial-mesenchymal transition of renal cell carcinoma through autophagy-dependent Wnt/β-catenin signaling
por: Fan, Yizeng, et al.
Publicado: (2020)

Silibinin inhibits the migration, invasion and epithelial-mesenchymal transition of prostate cancer by activating the autophagic degradation of YAP
por: Dan, Weichao, et al.
Publicado: (2022)

RHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer
por: Miao, Fei, et al.
Publicado: (2017)

Apatinib inhibits macrophage-mediated epithelial–mesenchymal transition in lung cancer
por: Liu, Shuliang, et al.
Publicado: (2018)

Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response
por: Zeng, Hao, et al.
Publicado: (2022)

Classification of Circulating Tumor Cells by Epithelial-Mesenchymal Transition Markers
por: Wu, Shiyang, et al.
Publicado: (2015)

MiR-924 as a tumor suppressor inhibits non-small cell lung cancer by inhibiting RHBDD1/Wnt/β-catenin signaling pathway
por: Wang, Huaishi, et al.
Publicado: (2020)

GC-1 mRHBDD1 knockdown spermatogonia cells lose their spermatogenic capacity in mouse seminiferous tubules
por: Wang, Yong, et al.
Publicado: (2009)

Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial–mesenchymal transition
por: Lin, Steven H, et al.
Publicado: (2014)

Inhibition of MiR-10b Restrains the Migration and Epithelial-Mesenchymal Transition of Lung Cells by Targeting LATS2 via TAZ Pathway
por: Yang, Yunlong, et al.
Publicado: (2020)

20(S)‐ginsenoside‐Rg3 reverses temozolomide resistance and restrains epithelial‐mesenchymal transition progression in glioblastoma
por: Chen, Zheng, et al.
Publicado: (2018)

AM251 Suppresses Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells
por: Yoshinaga, Tomoyo, et al.
Publicado: (2016)

RHBDD1 promotes proliferation, migration, invasion and EMT in renal cell carcinoma via the EGFR/AKT signaling pathway
por: Li, Mingyang, et al.
Publicado: (2021)

Silencing of RAD51AP1 suppresses epithelial–mesenchymal transition and metastasis in non‐small cell lung cancer
por: Wu, Yuanyuan, et al.
Publicado: (2019)

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells
por: Qin, Yuan, et al.
Publicado: (2015)

The Effect of Suppression Taurine on Relocation and Epithelial-Mesenchymal Transition in Mankind Lung Cancer Cells
por: Deng, Yongyan, et al.
Publicado: (2021)

Silibinin Regulates Tumor Progression and Tumorsphere Formation by Suppressing PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Cells
por: Rugamba, Alexis, et al.
Publicado: (2021)

Cycloartocarpin Inhibits Migration through the Suppression of Epithelial-to-Mesenchymal Transition and FAK/AKT Signaling in Non-Small-Cell Lung Cancer Cells
por: Tungsukruthai, Sucharat, et al.
Publicado: (2022)

RETRACTED ARTICLE: Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-133a Restrains Myocardial Fibrosis and Epithelial–Mesenchymal Transition in Viral Myocarditis Rats Through Suppressing MAML1
por: Li, Qiming, et al.
Publicado: (2021)

Retraction Note: Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-133a Restrains Myocardial Fibrosis and Epithelial–Mesenchymal Transition in Viral Myocarditis Rats Through Suppressing MAML1
por: Li, Qiming, et al.
Publicado: (2022)

Triptolide suppresses the growth and metastasis of non-small cell lung cancer by inhibiting β-catenin-mediated epithelial–mesenchymal transition
por: Deng, Qiu-di, et al.
Publicado: (2021)

Withaferin A inhibits Epithelial to Mesenchymal Transition in Non-Small Cell Lung Cancer Cells
por: Kyakulaga, Al Hassan, et al.
Publicado: (2018)

RBP2 Induces Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer
por: Wang, Shikun, et al.
Publicado: (2013)

Impact of Brachyury on epithelial-mesenchymal transitions and chemosensitivity in non-small cell lung cancer
por: XU, KE, et al.
Publicado: (2015)

Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity
por: Groves, Sarah M., et al.
Publicado: (2023)

Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer
por: Bosch-Barrera, Joaquim, et al.
Publicado: (2021)

Retracted: The Effect of Suppression Taurine on Relocation and Epithelial-Mesenchymal Transition in Mankind Lung Cancer Cells
por: Healthcare Engineering, Journal of
Publicado: (2023)

Cypripedin diminishes an epithelial-to-mesenchymal transition in non-small cell lung cancer cells through suppression of Akt/GSK-3β signalling
por: Treesuwan, Surassawadee, et al.
Publicado: (2018)

MicroRNA-4458 suppresses migration and epithelial–mesenchymal transition via targeting HMGA1 in non-small-cell lung cancer cells
por: Ma, Yu, et al.
Publicado: (2019)

Oridonin inhibits the migration and epithelial‐to‐mesenchymal transition of small cell lung cancer cells by suppressing FAK‐ERK1/2 signalling pathway
por: Xu, Linhao, et al.
Publicado: (2020)

Silibinin Suppresses the Hyperlipidemic Effects of the ALK-Tyrosine Kinase Inhibitor Lorlatinib in Hepatic Cells
por: Verdura, Sara, et al.
Publicado: (2022)

Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer
por: Zeng, Yong, et al.
Publicado: (2020)

Neighbor cells restrain furrowing during epithelial cytokinesis
por: Landino, Jennifer, et al.
Publicado: (2023)

6,6′-Bieckol induces apoptosis and suppresses TGF-β-induced epithelial-mesenchymal transition in non-small lung cancer cells
por: Li, Yongxin, et al.
Publicado: (2021)

Rotenone restrains the proliferation, motility and epithelial–mesenchymal transition of colon cancer cells and the tumourigenesis in nude mice via PI3K/AKT pathway
por: Xue, Wusong, et al.
Publicado: (2020)

Rotenone restrains colon cancer cell viability, motility and epithelial-mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway
por: Xiao, Wenbo, et al.
Publicado: (2020)

CTEN induces epithelial-mesenchymal transition (EMT) and metastasis in non small cell lung cancer cells
por: Lu, Xiangdong, et al.
Publicado: (2018)

Epithelial-mesenchymal Transition and Cell Invasion
por: Son, Hwajin, et al.
Publicado: (2010)

MARVELD3 inhibits the epithelial‐mesenchymal transition and cell migration by suppressing the Wnt/β‐catenin signaling pathway in non–small cell lung cancer cells
por: Li, Shirong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8h2lp126mj2b118ph47navv7am