HIF-1α-dependent miR-424 induction confers cisplatin resistance on bladder cancer cells through down-regulation of pro-apoptotic UNC5B and SIRT4

BACKGROUND: Chemo-resistance of bladder cancer has been considered to be one of the serious issues to be solved. In this study, we revealed pivotal role of miR-424 in the regulation of CDDP sensitivity of bladder cancer cells. METHODS: The cytotoxicity of cisplatin and effect of miR-424 were assesse...

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Detalles Bibliográficos
Autores principales: Yu, Meng, Ozaki, Toshinori, Sun, Dan, Xing, Haotian, Wei, Baojun, An, Jun, Yang, Jieping, Gao, Ying, Liu, Shuangjie, Kong, Chuize, Zhu, Yuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285474/
https://www.ncbi.nlm.nih.gov/pubmed/32522234
http://dx.doi.org/10.1186/s13046-020-01613-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285474/
https://www.ncbi.nlm.nih.gov/pubmed/32522234
http://dx.doi.org/10.1186/s13046-020-01613-y

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