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Transmission characteristics of heterozygous cases of Creutzfeldt-Jakob disease with variable abnormal prion protein allotypes
In the human prion disease Creutzfeldt-Jakob disease (CJD), different CJD neuropathological subtypes are defined by the presence in normal prion protein (PrP(C)) of a methionine or valine at residue 129, by the molecular mass of the infectious prion protein PrP(Sc), by the pattern of PrP(Sc) deposit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285538/ https://www.ncbi.nlm.nih.gov/pubmed/32517816 http://dx.doi.org/10.1186/s40478-020-00958-x |