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Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCε pathway in a rat model of neonatal HIE

BACKGROUND: Hypoxic-ischemic encephalopathy (HIE) is a life-threatening cerebrovascular disease. Neuroinflammation plays an important role in the pathogenesis of HIE, in which microglia are key cellular mediators in the regulation of neuroinflammatory processes. Colony-stimulating factor 1 (CSF1), a...

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Detalles Bibliográficos
Autores principales: Hu, Xiao, Li, Shirong, Doycheva, Desislava Met, Huang, Lei, Lenahan, Cameron, Liu, Rui, Huang, Juan, Xie, Shucai, Tang, Jiping, Zuo, Gang, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285566/
https://www.ncbi.nlm.nih.gov/pubmed/32522286
http://dx.doi.org/10.1186/s12974-020-01862-w