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Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCε pathway in a rat model of neonatal HIE
BACKGROUND: Hypoxic-ischemic encephalopathy (HIE) is a life-threatening cerebrovascular disease. Neuroinflammation plays an important role in the pathogenesis of HIE, in which microglia are key cellular mediators in the regulation of neuroinflammatory processes. Colony-stimulating factor 1 (CSF1), a...
Autores principales: | Hu, Xiao, Li, Shirong, Doycheva, Desislava Met, Huang, Lei, Lenahan, Cameron, Liu, Rui, Huang, Juan, Xie, Shucai, Tang, Jiping, Zuo, Gang, Zhang, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285566/ https://www.ncbi.nlm.nih.gov/pubmed/32522286 http://dx.doi.org/10.1186/s12974-020-01862-w |
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