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Modulating pyrimidine ribonucleotide levels for the treatment of cancer
By providing the necessary building blocks for nucleic acids and precursors for cell membrane synthesis, pyrimidine ribonucleotides are essential for cell growth and proliferation. Therefore, depleting pyrimidine ribonucleotide pools has long been considered as a strategy to reduce cancer cell growt...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285601/ https://www.ncbi.nlm.nih.gov/pubmed/33020720 http://dx.doi.org/10.1186/s40170-020-00218-5 |