Remodelling of the bone marrow microenvironment by stromal hyaluronan modulates the malignancy of breast cancer cells

BACKGROUND: Hyaluronan (HA) is an abundant component of the bone marrow (BM) extracellular matrix. Here, we investigated the abnormal deposition of HA in the BM microenvironment and its remodelling in mediating the malignancy of breast cancer cells (BCCs). METHODS: BCCs were transplanted into nude m...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoyan, Shi, Xiaoxing, Liu, Yiwen, He, Yiqing, Du, Yan, Zhang, Guoliang, Yang, Cuixia, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285718/
https://www.ncbi.nlm.nih.gov/pubmed/32517712
http://dx.doi.org/10.1186/s12964-020-00592-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285718/
https://www.ncbi.nlm.nih.gov/pubmed/32517712
http://dx.doi.org/10.1186/s12964-020-00592-z

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