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Severe chronic kidney disease environment reduced calcium-sensing receptor expression in parathyroid glands of adenine-induced rats even without high phosphorus diet

BACKGROUND: Chronic kidney disease (CKD) disrupts mineral homeostasis and its main underlying cause is secondary hyperparathyroidism (SHPT). We previously reported that calcium-sensing receptor (CaSR) mRNA and protein expression in parathyroid glands (PTGs) significantly decreased in a CKD rat model...

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Detalles Bibliográficos
Autores principales: Uchiyama, Taketo, Ohkido, Ichiro, Nakashima, Akio, Saito, Yatsumu, Okabe, Masataka, Yokoo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285719/
https://www.ncbi.nlm.nih.gov/pubmed/32517664
http://dx.doi.org/10.1186/s12882-020-01880-z