Microbe‐Dependent Exacerbated Alveolar Bone Destruction in Heterozygous Cherubism Mice

Cherubism (OMIM#118400) is a craniofacial disorder characterized by destructive jaw expansion. Gain‐of‐function mutations in SH3‐domain binding protein 2 (SH3BP2) are responsible for this rare disorder. We have previously shown that homozygous knock‐in (KI) mice (Sh3bp2 (KI/KI)) recapitulate human c...

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Detalles Bibliográficos
Autores principales: Kittaka, Mizuho, Yoshimoto, Tetsuya, Schlosser, Collin, Kajiya, Mikihito, Kurihara, Hidemi, Reichenberger, Ernst J, Ueki, Yasuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285758/
https://www.ncbi.nlm.nih.gov/pubmed/32537546
http://dx.doi.org/10.1002/jbm4.10352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285758/
https://www.ncbi.nlm.nih.gov/pubmed/32537546
http://dx.doi.org/10.1002/jbm4.10352

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